Listar Artículo en revista de investigación por autor "0000-0003-1760-6116"
Mostrando ítems 1-20 de 24
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A Full Set of In Vitro Assays in Chitosan/Tween 80 Microspheres Loaded with Magnetite Nanoparticles
Garcia Casillas, Perla Elvia; Chapa, Christian; 148925; 183042; Roacho Pérez, Jorge Alberto; Sánchez Dominguez, Celia Nohemi (2021-01-27)Microspheres have been proposed for different medical applications, such as the delivery of therapeutic proteins. The first step, before evaluating the functionality of a protein delivery system, is to evaluate their ... -
A Review on the Efficacy and Safety of Nab-Paclitaxel with Gemcitabine in Combination with Other Therapeutic Agents as New Treatment Strategies in Pancreatic Cancer
Chapa, Christian (2022-02-22)Pancreatic cancer has one of the highest mortality rates among cancers, and a combination of nab-paclitaxel with gemcitabine remains the cornerstone of first-line therapy. However, major advances are required to achieve ... -
Adsorption of serum protein in chitosan-coated and polyethyleneimine-coated magnetite nanoparticles
Chapa, Christian (2021-11-03)Magnetite (Fe3O4) nanoparticles provide several possibilities for a compelling platform for medical applications due to their magnetic properties. In the same way, functionalization with polymers provides several properties ... -
Avances de la Tecnología Organ-on-a-chip de Riñón hacia Dispositivos de Remplazo de la Función Renal
Chapa, Christian (2021-02-22)La enfermedad renal crónica (ERC) requiere de terapia de reemplazo renal en su última fase, la cual incluye diálisis en cualquiera de sus modalidades y trasplante de riñón. Hasta ahora, la mejor opción es el trasplante ... -
Bactericidal activity of silver nanoparticles in drug-resistant bacteria
Chapa, Christian (2023-05-02)Bacterial resistance to multiple drugs is a worldwide problem that afflicts public health. Various studies have shown that silver nanoparticles are good bactericidal agents against bacteria due to the adherence and penetration ... -
Citrulline malate transdermal delivery through integrating into polyvinyl alcohol (PVA) nanofibers
Garcia Casillas, Perla Elvia; Chapa, Christian; Martinez, Carlos Alberto; López-Ramírez, Elizabeth; Escobedo-González, Rene Gerardo; Nicolás Vázquez, María Inés; Medellín-Rodríguez, Francisco (2021-06-08)Citrulline Malate (CM) is a pre-workout energy supplement, frequently used to reduce fatigue in sports that require high levels of energy. Typically, oral intake should occur at least 2 h before undertaking sport, in order ... -
Cytotoxic efect of polyvinyl alcohol‑magnetite composite
Chapa, Christian; Olivas Armendariz, Imelda; Garcia-Casillas, Perla Elvia; 125330 (2023-08-31)Polymeric hydrogel is a promising candidate for drug delivery applications due to its ability to encapsulate and release drugs. Incorporating magnetic particles enables controlled and specifc release, providing sustained ... -
Detection of HER2 through Antibody Immobilization Is Influenced by the Properties of the Magnetite Nanoparticle Coating
Villegas-Serralta, Enrique (2018-04-02)Considerable effort has been focused on improving the control of size, shape, and surface modifications to detect proteins. The purpose of this study was to compare the efficiencies of aminosilane-coated magnetite (As-M) ... -
Effect of Aminosilane Nanoparticle Coating on Structural and Magnetic Properties and Cell Viability in Human Cancer Cell Lines
Elizalde Galindo, Jose Trinidad; Garcia Casillas, Perla Elvia; Chapa, Christian; 199242; Flores Urquizo, Israel Alejandro; Hernández García, Tomás Constantino; Lugo Loredo, Shadai; Stevens Barrón, Jazmín Cristina (2022-07-15)Magnetic nanoparticle interfaces have aroused great scientific research interest in the biomedical area since the interaction of cells or biomolecules with nanoparticles is determined by the surface properties. Currently, ... -
Effect of physiological fluid on the photothermal properties of gold nanostructured
Farias, Rurik; Chapa, Christian; 228153; 229137; Amézaga González, María Fernanda; Avila Orta, Caros; Garcia Casillas, Perla Elvia (2023-05-06) -
Enhancing the Cytocompatibility of Cobalt-Iron Ferrite Nanoparticles Through Chemical Substitution and Surface Modification
Chapa, Christian (2023-05-28)Due to their potential in numerous interdisciplinary fields, such as drug delivery, hyperthermia, and magnetic resonance imaging, magnetic nanoparticles have attracted widespread attention. In this study, cobalt ferrite ... -
Functional tests of an in vitro maintenance system prototype type organ-on-chip for skeletal muscle
Chapa, Christian (2021-07-06)Due to the necessity to develop new systems which maintain the proper conditions for cell growth and cell interaction in vitro, this work has focused on the characterisation of two models of maintenance system prototypes ... -
Gold Nanoparticles as Drug Carriers: The Role of Silica and PEG as Surface Coatings in Optimizing Drug Loading
Chapa, Christian; 125295; Carreón González, José Luis; Garcia Casillas, Perla Elvia (2023-02-15)The use of gold nanoparticles as drug delivery systems has received increasing attention due to their unique properties, such as their high stability and biocompatibility. However, gold nanoparticles have a high affinity ... -
Immunotherapy in Combination with Chemotherapy for Triple-Negative Breast Cancer
Chapa, Christian; 168435; Meléndez-Solano, Elizabeth; Stevens Barrón, Jazmín Cristina (2023-05-17)Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer that lacks estrogen and progesterone receptors and does not overexpress the human epidermal growth factor receptor 2 (HER2). Previous treatment ... -
Lipid nanoparticles for gene therapy in ocular diseases
Chapa, Christian (2023-02-15)Objectives Lipid nanoparticles, as a nucleic acid delivery system, have been used as an alternative to treat ocular diseases, since they can cross the ocular barrier and efficiently transfecting nucleic acids to various ... -
Magnetite nanoparticles coated with PEG 3350-tween 80: In vitro characterization using primary cell cultures
Chapa, Christian (2020-02-02)Some medical applications of magnetic nanoparticles require direct contact with healthy tissues and blood. If nanoparticles are not designed properly, they can cause several problems, such as cytotoxicity or hemolysis. A ... -
Nanoparticles for death‑induced gene therapy in cancer (Review)
Roacho Pérez, Jorge A (2018-01-01)Due to the high toxicity and side effects of the use of traditional chemotherapy in cancer, scientists are working on the development of alternative therapeutic technologies. An example of this is the use of death‑induced ... -
Nanoparticles for death‑induced gene therapy in cancer (Review)
Roacho Pérez, Jorge A (2018-01)Due to the high toxicity and side effects of the use of traditional chemotherapy in cancer, scientists are working on the development of alternative therapeutic technologies. An example of this is the use of death‑induced ... -
Physicochemical properties of chitosan–magnetite nanocomposites obtained with different pH
Chapa, Christian (2021-08-10)The physicochemical properties of the nanoparticle surface determine the performance of nanocomposites in biomedical applications such as their biodistribution and pharmacokinetics. The physicochemical properties of chitosan, ... -
Recycled glass and Ce‐Doped‐Y3Al5O12 nanoparticles phosphor‐in‐glass for white light‐emitting diodes applications
Chapa, Christian (2020-06-07)A series of nanocomposites of recycled soda‐lime glass from a glass container and Y3Al5O12:Ce3+ (YAG:Ce) phosphor nanoparticles are fabricated by the two‐step low‐temperature co‐sintering technology. A transparent glass ...