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dc.contributor.authorCarrillo, Amanda
dc.date.accessioned2024-10-15T16:17:56Z
dc.date.available2024-10-15T16:17:56Z
dc.date.issued2024-06-22es_MX
dc.identifier.urihttps://cathi.uacj.mx/20.500.11961/28873
dc.description.abstractChronic renal insufficiency has been a high-incidence disease around the world in recent years. With the lack of devices to detect these illnesses opportunely, developing urea biosensors is imperative. This work reports the application of copper sulfide (CuS) thin films deposited via a chemical bath and Bioglass 45S5/titanium dioxide nanoparticles thin films in a urea flexible biosensor. The Bioglass 45S5 was deposited over CuS and applied onto polyethylene naphthalate (PEN) and polyethylene terephthalate (PET) with indium tin oxide (ITO) substrates. The systems PEN/CuS/Bioglass 45S5.TiO2 NpS and PET/ITO/CuS/ Bioglass 45S5.TiO2 were characterized optically by UV-Vis. The CuS presented an absorption border around 600 nm and a decrease in transmittance percentage by adding Bioglass. Scanning Electron Microscopy carried out the microstructural characterization; both systems displayed a porous morphology featuring channels suitable for immobilizing the enzyme. The sensors showed a resistive behavior based on the current-voltage curve. The urease enzyme was immobilized by adsorption. The optical changes after adding urease were measured by UV-Vis, obtaining ammonia from the reaction between urease and urea, showing an absorption border around 850 nm. Changes in urea concentrations between 1 and 10 mM caused an increase in resistivity in both samples, obtaining a sensitivity of 12.887 kΩ/sq/mM and 12.411 kΩ/sq/mM, and a linearity of 0.9946 % and 0.9601 % for the samples deposited over PEN and PET ITO, respectively. A Cole-Cole plot showed a behavior corresponding to an equivalent circuit composed of a parallel combination of a resistor and a capacitor in series with a phase constant element; this latter could be attributed to the measurement electrodes. Each sensor was implemented in a Wheatstone bridge. A voltage decrease was obtained for the sample deposited over PET ITO, with a sensitivity of −102.7 mV/mM, and a voltage increase was obtained in the sample deposited over PEN, with a sensitivity of 30.5 mV/mM.es_MX
dc.description.urihttps://www.sciencedirect.com/science/article/abs/pii/S0925838824018966es_MX
dc.language.isoenes_MX
dc.relation.ispartofProducto de investigación IITes_MX
dc.relation.ispartofInstituto de Ingeniería y Tecnologíaes_MX
dc.rightsAtribución-NoComercial-SinDerivadas 2.5 México*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/mx/*
dc.subject.otherinfo:eu-repo/classification/cti/7es_MX
dc.titleFlexible urea biosensor based on CuS/Bioglass 45S5.TiO2 Nps thin filmses_MX
dc.typeArtículoes_MX
dcterms.thumbnailhttp://ri.uacj.mx/vufind/thumbnails/rupiiit.pnges_MX
dcrupi.institutoInstituto de Ingeniería y Tecnologíaes_MX
dcrupi.cosechableSies_MX
dcrupi.volumen1002es_MX
dcrupi.nopagina1-11es_MX
dc.identifier.doihttps://doi.org/10.1016/j.jallcom.2024.175309es_MX
dc.contributor.coauthorGonzalez Landaeta, Rafael Eliecer
dc.contributor.alumno220734es_MX
dc.journal.titleJournal of Alloys and Compoundses_MX
dc.contributor.alumnoprincipal220734es_MX
dcrupi.pronacesSaludes_MX


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