Bioactividad y biocompatibilidad de compósitos de zirconia estabilizada con Y/ hidroxiapatita-Cu, Fosfato Tricálcico-Ag o Fosfato Tricálcico-Ga
Resumen
The biological compatibility of bone and dental implants is limited, since it is placed until a long time
after it has been implanted, due to its low resistance
of infections attributed to a quick degradation of the
implant which is present in the physiological fluids.
Therefore, in this investigation, hydroxyapatite-zirconia
(HA-ZrO2) composite materials were developed, where
zirconia was stabilized with yttrium and hydroxyapatite was doped with silver, copper and gallium, in
order to give biological properties to the composite
that the zirconia does not present. Each component
of the composite material has different characteristics; such as hydroxyapatite (HA) that provides it a
bioactive behavior, On the other hand ZrO2
stabilized
with yttrium gives it excellent resistance; otherwise,
Ag, Ga and Cu provide antimicrobial properties. To
obtain these systems, the materials were synthesized
by the Pechini method and chemical precipitation.
Afterward the compounds were obtained and tested
by bioactivity tests, hemolysis, cell viability studies by
the MTT method and osteoblast adhesion by staining,
hence there were obtained bioactive, non-hemolytic,
non-toxic materials with cell adhesion to the composite.
and as a result of that, these awesome materials can be
useful for dental implants.