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dc.contributor.authorMartel-Estrada, Santos-Adriana
dc.date.accessioned2019-01-10T16:36:38Z
dc.date.available2019-01-10T16:36:38Z
dc.date.issued2018-12-12
dc.identifier.urihttp://cathi.uacj.mx/20.500.11961/5496
dc.description.abstractBACKGROUND:The development of biomaterial scaffolds and implementation of tissue engineering techniques are necessary. Therefore, Polycaprolactone/Sodium Hyaluronate/Multiwalled Carbon Nanotubes/Extract of Mimosa tenuiflora composites have been produced by a thermally-induced phase separation method. OBJECTIVE:The objective of this research was to evaluate the in vitro bioactivity and in vitro biocompatibility of the composites. METHODS:The in vitro bioactivity of the composites was assessed by soaking them in simulated body fluid for 7, 14, 21, and 28 days. The structure and composition of the composites were analyzed using scanning electron microscopy coupled with energy dispersive spectroscopy and Fourier transform infrared spectroscopy. Also, the in vitro biocompatibility of the composites was evaluated by means of alkaline phosphatase activity of the osteoblasts and by measuring the metabolic activity of the cells using MTT assay. RESULTS:The results show a porous and interconnected morphology with enhanced bioactivity. It was observed that the incorporation of Mimosa tenuiflora in the composites promotes increased viability of osteoblasts in the scaffolds. CONCLUSIONS:The results show the efficiency of bioactive and biocompatible composites and their potential as candidates for tissue engineering applications.es_MX
dc.description.urihttps://content.iospress.com/articles/bio-medical-materials-and-engineering/bme181036es_MX
dc.language.isoenes_MX
dc.relation.ispartofProducto de investigación IADAes_MX
dc.relation.ispartofInstituto de Arquitectura Diseño y Artees_MX
dc.subjectBioactive materialses_MX
dc.subjectpolycaprolactonees_MX
dc.subjectsodium Hyaluronatees_MX
dc.subjectMWCNTes_MX
dc.subjectMimosa Tenuifloraes_MX
dc.subjectSBFes_MX
dc.subjectMTT assayes_MX
dc.subject.otherinfo:eu-repo/classification/cti/7es_MX
dc.titleEvaluation of in vitro bioactivity and in vitro biocompatibility of Polycaprolactone/Hyaluronic acid/Multiwalled Carbon Nanotubes/Extract from Mimosa Tenuiflora compositeses_MX
dc.typeArtículoes_MX
dcterms.thumbnailhttp://ri.uacj.mx/vufind/thumbnails/rupiiada.pnges_MX
dcrupi.institutoInstituto de Arquitectura Diseño y Artees_MX
dcrupi.cosechableSies_MX
dcrupi.nopagina1-13es_MX
dc.identifier.doi10.3233/BME-181036es_MX
dc.contributor.coauthorLimón-Martínez, Rocío Janeth
dc.contributor.coauthorOlivas Armendáriz, Imelda
dc.contributor.coauthorSosa Rodarte, Estefanía
dc.contributor.coauthorRodríguez Rodríguez, Carlos Iván
dc.contributor.coauthorHernández Paz, Juan Francisco
dc.contributor.coauthorAcosta-Torres, Laura
dc.contributor.coauthorGarcía-Contreras, René
dc.contributor.coauthorSantos-Rodríguez, Elí
dc.journal.titleBio-Medical Materials and Engineeringes_MX
dc.lgacBIOMATERIALES Y SISTEMAS DE LIBERACIÓN DE FÁRMACOSes_MX
dc.cuerpoacademicoIngeniería Tisular y Medicina Regenerativaes_MX


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