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AutorLoyola-Rodriguez, Juan Pablo
Accedido2019-09-05T18:49:32Z
Disponible2019-09-05T18:49:32Z
Fecha de publicación2019-07-01
Identificador de objeto (URI)http://cathi.uacj.mx/20.500.11961/8165
Resumen/AbstractBackground: The main microorganism associated with the failure of endodontic treatments is Enterococcus faecalis. Although several endodontic therapeutics have demonstrated antimicrobial activity against E. faecalis, the antimicrobial effectiveness of chitosan (CsNPs) and silver nanoparticles (AgNPs) included into conventional endodontic sealers for endodontic therapies is still unclear. Aim: The objective of this study was to evaluate the antibacterial activity increment (AAI) of endodontic sealers containing CsNPs and AgNPs as well as some chemical components against E. faecalis by direct contact assays. Methods: CsNPs and AgNPs were synthesized by reduction and ionic gelation methods, respectively. Nanoparticles were characterized by dynamic light scattering and energy dispersive X-ray analysis. The bactericidal activity was tested on monolayers on agar plates and collagen membrane surface assays against E. faecalis. Results: The size of CsNPs was 70.6±14.8 nm and zeta potential was 52.0±5.4 mV; the size of AgNPs was 54.2±8.5 nm, and zeta potential was –48.4±6.9 mV. All materials, single or combined, showed an AAI, especially when CsNPs, chlorhexidine (Chx), and the combination of CsNPs-Chx were added. However, the combination of CsNPs-Chx showed the highest (55%) AAI, followed by Chx (35.5%) and CsNPs (11.1%), respectively. There was a significant statistical difference in all comparisons (p < 0.05). Tubliseal (40%) and AH Plus (32%) sealants showed a higher AAI on E. faecalis in the monolayer test and collagen membrane assay analyzed by scanning electron microscopy. Conclusions: Tubliseal and AH plus sealers combined with nanoparticles, especially CsNPs-Chx, could be used for conventional endodontic treatments in the control of E. faecalis bacteria.es_MX
Descripción URIhttps://journals.sagepub.com/doi/10.1177/2280800019851771es_MX
Idioma ISOen_USes_MX
Referencias físicas o lógicasProducto de investigación ICBes_MX
Referencias físicas o lógicasInstituto de Ciencias Biomédicases_MX
TemaEnterococcus faecalis, endodontic sealers, silver nanoparticles, chitosan nanoparticles, chlorhexidinees_MX
Área de conocimiento CONACYTinfo:eu-repo/classification/cti/3es_MX
TítuloAntimicrobial activity of endodontic sealers and medications containing chitosan and silver nanoparticles against Enterococcus faecalises_MX
Tipo de productoArtículoes_MX
Imagen repositoriohttp://ri.uacj.mx/vufind/thumbnails/rupiicb.pnges_MX
Instituto (dcrupi)Instituto de Ciencias Biomédicases_MX
CosechableSies_MX
No. de revista1es_MX
Volumen1es_MX
Rango de páginas1-9es_MX
Identificador DOIhttps://doi.org/10.1177/228080001985177es_MX
CoautorTorres-Mendez, Fernando
CoautorEspinosa Cristobal, Leon Francisco
CoautorGarcia-Cortez, Jose Obed
CoautorLoyola-Leyva, Alejandra
CoautorJavier-Gonzalez, Francisco
CoautorSoto-Barreras, Uriel
CoautorNieto-Aguilar, Renato
CoautorContreras-Palma, Guillermo
Título de revistaJournal of Applied Biomaterials & Functional Materialses_MX
Línea de investigaciónInvestigación en materiales nanoestructurados.es_MX
Cuerpo académicoInvestigación Estomatológica-Biomédicaes_MX


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