Listar ICB Artículo en revista de investigación por autor "0000-0002-6398-7274"
Mostrando ítems 1-16 de 16
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A novel approach to trypsin inhibition by flavonoids
Alvarez-Parrilla, Emilio (2021-06-30)Trypsin is a key protease related to digestion and absorption of proteins, which its inhibition must be studied when natural compounds, such as flavonoids, are used as part of alternative treatments for obesity and ... -
Aspectos estructurales y funcionales de la N-Succinil-L, L-diaminopimelato desuccinilasa, una enzima clave para el crecimiento bacteriano y un blanco para el control antimicrobiano
Diaz Sanchez, Angel Gabriel (2019-10-17)Aspectos estructurales y funcionales de la N-Succinil-L, L-diaminopimelato desuccinilasa, una enzima clave para el crecimiento bacteriano y un blanco para el control antimicrobianoNota: Artículo recibido el 6 de abril del ... -
Blood mononuclear cells as speculum of emotional stress analyzed by synchrotron infrared spectroscopy and a nootropic drug
Martinez-Martinez, Alejandro (2018-11)Chronic psychological stress is an important public health issue which generates behavioral changes, anxiety, immunosuppression and oxidative damage. Piracetam is a cognitive enhancer, at cellular level it protects from ... -
Comparación de métodos de extracción de proteínas de cerebro y linfocitos de rata
Gonzalez Fernandez, Raquel (2018-11-26)En este trabajo se compararon tres técnicas de extracción de proteínas actualmente empleadas en proteómica, para determinar la más eficiente para realizar electroforesis bidimensional (2-DE) en tejido cerebral y ... -
Contenido de polifenólicos, actividad antioxidante y antimicrobiana de la raíz de ibervillea sonorae
Núñez-Gastélum, José Alberto (2018-07-09)El objetivo del presente estudio fue evaluar el contenido de polifenólicos, capacidad antioxidante y antimicrobiana de la raíz de Ibervillea sonorae proveniente del estado de Sonora. Se utilizaron cuatro muestras representativas ... -
Estudios bioquímicos y de inhibición recombinantes: El caso de la enzima DapE
Diaz Sanchez, Angel Gabriel (2020-06-01) -
FDA-approved thiol-reacting drugs that potentially bind into the SARS-CoV-2 main protease, essential for viral replication
Diaz Sanchez, Angel Gabriel (2020-05-14)Emergent novel SARS-CoV-2 is responsible for the current pandemic outbreak of severe acute respiratory syndrome with high mortality among the symptomatic population worldwide. Given the absence of a current vaccine or ... -
Inhibición de lipasa pancreática por flavonoides: importancia del doble enlace C2= C3 y la estructura plana del anillo C
Alvarez-Parrilla, Emilio (2020-08-07)Lipasa pancreática es una enzima clave en el metabolismo de lípidos. Los flavonoides son compuestos bioactivos de gran relevancia debido a sus interacciones con enzimas digestivas. Se evaluó la actividad de lipasa pancreática ... -
Inhibition of α-amylase by flavonoids: Structure activity relationship (SAR)
Martinez-Gonzalez, Alejandra I. (2019)Flavonoids are recognized to regulate animals' food digestion processes trough interaction with digestive enzymes. The binding capacity of hesperetin (HES), luteolin (LUT), quercetin (QUE), catechin (CAT) and rutin (RUT) ... -
Interaction of N-succinyl diaminopimelate desuccinylase with orphenadrine and disulfiram
Diaz Sanchez, Angel Gabriel (2020-12-15)The emergence of multiresistant, often persistent, pathogenic bacteria emphasizes the need for a continuous identification of new pharmacological targets of enzymatic nature, and the development of selective inhibitors ... -
Interaction of N-succinyl-diaminopimelate desuccinylase with flavonoids
Diaz Sanchez, Angel Gabriel (2020-10-01)DapE is an enzyme that belongs to the meso-diaminopimelate/Lysine pathway. It is recognized as an antimicrobial target, hence compounds that inhibit its catalytic activity are required. The principal features considered ... -
Proanthocyanidins with a low degree of polymerization are good inhibitors of digestive enzymes because of their ability to form specific interactions: a hypothesis
Vázquez-Flores, Alma A. (2018-12)Inhibition of target digestive enzymes is an accepted strategy to prevent diseases such as obesity and diabetes. Proanthocyanidins (PACs) are known for their ability to bind, inhibit, and precipitate enzymes, which makes ... -
Psychological distress and lack of PINK1 promote bioenergetics alterations in peripheral blood mononuclear cells
Martinez-Martinez, Alejandro (2020-06-17)Psychological distress induces oxidative stress and alters mitochondrial metabolism in the nervous and immune systems. Psychological distress promotes alterations in brain metabolism and neurochemistry in wild-type (WT) ... -
Screening of the physical and structural properties of chitosan-polycaprolactone films added with moringa oleifera leaf extract
Núñez-Gastélum, José Alberto (2019-01-01)Physico-structural properties of biodegradable films of chitosan and polycaprolactone (PCL) added with Moringa oleifera leaf extract were determined. The films were analyzed for thickness, transparency, solubility, Fourier ... -
Seed germination and sprouts production of Moringa oleifera: A potential functional food?
Núñez-Gastélum, José Alberto (2023-05)Moringa oleifera is a plant valued for its properties and applications in Ethnomedicine. It is cultivated in India, tropical Africa, and America; some regions use their different tissues as food supplements. Although ... -
Self-assembled amphiphilic bipyridine and bisquinoline cisplatin analogues: synthesis and anticancer properties.
Diaz Sanchez, Angel Gabriel (2023-12-23)We report the synthesis and characterisation of two amphiphilic cisplatin analogues derived from bipyridine and bisquinoline modified with two 3-oxo-3,6,9,12-tetraoxadocosyl groups. The amphiphilic cisplatin analogues ...