Synthesis and Characterization of PVA-HEC Hydrogel: A New Proposal for the Reconstructive Treatment of Breast Cancer Survivors

Abstract

Women who suffer a radical mastectomy as a consequence of the treatment of breast cancer, lead with physical and psychic effects. The reconstruction of this important area of the human body in the female psyche was our goal to develop a new material that allows the reconstruction of the breast through the use of a biodegradable implant that supports the regeneration of the removed adipose tissue. For this, we selected a polymeric matrix of PVA-HEC that achieved the objective in animal models in 4 months. This work discusses the details of its synthesis and characterization to understand the mechanisms of interaction of this matrix with the organism.