MOST FREQUENT ORAL AND CRANIOFACIAL CLINICAL CHARACTERISTICS ASSOCIATED WITH SYNDROMES: A SYSTEMATIC REVIEW

Abstract

Syndrome is defined as a group of signs, symptoms and individual characteristics that appears simultaneously in a person or in a group of persons which are otherwise unrelated. According to the literature, it is estimated that approximately one in every 170 births present a syndrome of chromosomal origin globally. The etiology of these remains unknown in 60% of the cases. Syndromes present clinical characteristics at an anatomic, physiologic, and neurologic level that affect different regions, organs, and tissues, including the oral cavity and its associated craniofacial structures. Between 900 and 5000 syndromes of genetic origin were associated with dental, oral, and maxillofacial anomalies.